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Thank You All

Thank You All

“As we express our gratitude, we must never forget that the highest appreciation is not to utter words, but to live by them.” – JFK

Special Thanks to my Family and Friends for your Kind Words of Encouragment and Support…I thank God for the Strength, Knowledge and Wisdom to take on such a Task of Informing the Society on the Fascinating World of Biochemistry… I am much indebted to my lecturer for all the critism and knowledge of the subject matter…

Lastly I Thank You All My Bloggers/Followers for Your Continued Support…Words Cannot Express My Gratitude…

Video Review Two: NUCLEOTIDES

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This is one of the many videos created by a “youtuber” named of College Level Biochemistry: aaronsbiochemvideos. His videos are very much helpful and filled with animation and materials related to our course outline for Biol 1362. He utilizes the reccommended textbook LEHNINGER PRINICPLES OF BIOCHEMISTRY 5th Ed, and uses most of the diagrams and chart in the text in his videos making it easy for one to follow provide that they have a textbook.

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Please check the link below and Goodluck…Happy Studying 😀

http://www.youtube.com/user/aaronsbiochemvideos?feature=watch

Publish Paper #2: Can Brown adipose tissue regulate glucose homeostasis and insulin sensitivity???

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Brown adipose tissue (BAT) is known for its capacity to generate heat in response to cold or diet to maintain thermal balance. The regulated production of heat is called adaptive thermogenesis. BAT is the main tissue for this adaptive thermogenesis in rodents and most likely in human infants.

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Cold-stimulated adaptive thermogenesis in brown adipose tissue (BAT) to increase energy expenditure is suggested as a possible therapeutic target for the treatment of obesity. Scientist have recently shown high prevalence of BAT in adult humans, which was inversely related to body mass index (BMI) and body fat percentage (BF%), suggesting that obesity is associated with lower BAT activity.

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(http://themedicalbiochemistrypage.org/images/brownfatheat.jpg)

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(http://www.nature.com/nature/journal/v458/n7240/images/458839a-f1.2.jpg)

Brown adipose tissue (BAT) is known to function in the dissipation of chemical energy in response to cold or excess feeding, and also has the capacity to modulate energy balance. To test the hypothesis that BAT is fundamental to the regulation of glucose homeostasis, highly qualified scientist transplanted BAT from male donor mice into the visceral cavity of age- and sex-matched recipient mice. By 8–12 weeks following transplantation, the recipient mice had improved glucose tolerance, increased insulin sensitivity, lower body weight, decreased fat mass, and a complete reversal of high-fat diet–induced insulin resistance. Increasing the quantity of BAT transplanted into recipient mice further improved the metabolic effects of transplantation. BAT transplantation increased insulin-stimulated glucose uptake in vivo into endogenous BAT, white adipose tissue (WAT), and heart muscle but, surprisingly, not skeletal muscle. The improved metabolic profile was lost when the BAT used for transplantation was obtained from IL6–knockout mice, demonstrating that BAT-derived IL-6 is required for the profound effects of BAT transplantation on glucose homeostasis and insulin sensitivity. These findings reveal a previously under-appreciated role for BAT in glucose metabolism.

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A MicroPET Study Of Brown Adipose Tissue

Imaging(from left to right):control,obesity,and treatment group

(http://www.wmicmeeting.org/2010/Abstracts/forSystemUse/papers/images/0125_A.jpg)

REFERENCES

http://www.jci.org/articles/view/62308

RESEARCH ARTICLE

Stanford, Kristin I. , Roeland J.W. Middelbeek, Kristy L. Townsend, Ding An, Eva B. Nygaard, Kristen M. Hitchcox, Kathleen R. Markan, Kazuhiro Nakano, Michael F. Hirshman, Yu-Hua Tseng and Laurie J. Goodyear. Brown adipose tissue regulates glucose homeostasis and insulin sensitivity. Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA. Volume 123, Issue 1 (January 2, 2013). Accessed 12th April, 2013. http://www.jci.org/articles/view/62308

Open Book Exam…Really???

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How does one really have an ‘open book’ exam at the University level…well the name does not say it all unfortunately…there’s a catch!!! Obviously there were rules you had to obey… So I here I go…You we allowed to carry a half letter-size sheet with notes on any topic to aid in answering the questions in the exam. Seems only fair Right??? While many took this opportunity to carry notes…..others, like myself walked into the exam with nothing but a pen…Did I have any regrets? It’s 50/50, maybe if I had notes I would answered the questions in the alotted time but, looking for notes on the small sheet may have been time consuming as well…knowing my hand-writing.

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The exam was manageable to say the least…it did in fact cover all the topics throught the seimester and also gave me a good idea of what to expect in the final exam.

ImageHowever I was really disappointed with the time giving to do this exam. Repeaters and New Students were placed in separate classrooms for this exam. I believe that invigilators should learn to speak to the students….like really…you’re supervising a classroom of nervous students and you’ll speak as though you’re arguing…dont gotta be so harsh. Not to mention ‘We’ only got 40 minutes to do this exam. Doesn’t she own a watch??? Oh and the constant “whispering” in front the classroom…I am sorry but I was really annoyed at the fact that our exam time was so short…many didnt get to finish the exam. At 9:46 our exam finished, well for repeaters that is…as for the new students they were still in exam mode…and obviously they got full time. I am sure many felt the same fustration as I did after the exam…but what can I do about now….nothing!!! Can’t complain….clearly….oh well its all a learning experience…I’m still gonna “mash up” final exams…We all Are!!!

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VIDEO REVIEW ONE

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This was the very first video done by my lecturer on the topic of “The Cell.” Although the thought of watching a 40 minute seems a bit tedious to some many of you may find this video to be very interesting. If any of you looked at the course outline you would notice that the video stated exactly what we are to learn. I liked that the video was straight forward to the point…I was never “bored” or feeling the need to “x” of this video which has happeded to all of us. I must commend the use of slides in that they we not only easy to read but also the use of colours and illustration/imagary captured my attention. The Lecturer spoke fluently and with confidence giving me the assurance that he knows his stuff 😀

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A TYPICAL ANIMAL CELL

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A TYPICAL PLANT CELL

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PROKARYOTIC vs EUKARYOTIC CELLS

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ENDOSYMBIOTIC THEORY

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(http://online.santarosa.edu/homepage/cgalt/BIO10-Stuff/Ch13-Evolution/Endosymbiotic_Theory_of_Eukaryotic_origin-Lateral_Gene_Transfer.JPG)

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CHECK OUT THE LINK BELOW VIDEO “THE CELL” BiochemJM

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GOOD LUCK!!!

BIOLOGICAL MOLECULES WORD SEARCH

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O H K C D C S S O V E R R U Z A J T F D F E T N L 
X H E N A U L E W D C O M B O N A T I O N N R A A 
Y H O M L R D I I O N I M A X F L P Q B P I I H C 
G B Q F O I B T A D W O K Y Y M E P O Q V N P P I 
E I U L T G P O H C N L N T A P O Q K G Q A E T L 
N R I P E E L T N Y A E T V T L J T E B A L P P E 
S O E H P T O O R I D K M I T C M N K S A A T Y H 
H P D Y F X A S B Y N R D J U Q Z E X Z V L I R Y 
R R L U D D N R L I F E O V N Y N L T G V Y D T G 
Y O P L U I E R T S N P E G M G I F T I E N E A P 
P P U C E H H N N S K S W E E N T P V T S E L L U 
T X Z T Y G W W I Z B L S V T N R J C L F H F K H 
N Z O S E Q U E N C E U E D E X O A V F H P J O E 
I R Y Z V Z F U U E Y Q S S T J G H M J A D X C I 
P V U Q L T K T J N Y L A E H E E E P Q P I R A U 
X N G B P J C L V W N T G M E T N S V W Z C K U Y 
A A F E G U R S C E C X I J I I Y W Y G D A Q N Z 
R D Z X F W E M E Z W P W J T A M T Y M Y E S N J 
E R U T C U R T S S B W G K F D S M T M A U K V G 
G N I D L O F O X C A C T I V E L H B V U Y H Z E 
L B B X J Y L V Y T V K C V H L C S D R E C J A L 
Y F M D V A A B Q D D H K O X E N F G L B Y M S K 
N C G G A Q T Q K D S K F O W T X P V F Y O Z T L 
V X E D G N T E Y D D T I B M M G D U H V W R N T 
K D E U I S S Q W Z M T L B G V G N F C J R Q K T 

ACID
ACTIVE
AMINO
BOND
CARBON
COMBONATION
DIPEPTIDE
ENZYMES
FOLDING
GLYCINE
HELICAL
HEMOGLOBIN
HYDROGEN
NITROGEN
OXYGEN
PEPTIDE
PHENYLALANINE
POLYPEPTIDE
PROTEINS
SEQUENCE
SITE
STRUCTURE
SUBSTRATE
SULFUR
TRIPEPTIDE
TRYPTPHAN